Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Guanosine 3',5'-cyclic Monophosphate, 8-Bromo-, Sodium Salt
Cell-permeable cGMP analog that is more resistant to phosphodiesterases than cGMP.
MilliporeSigma™ Calbiochem™ TRPV4 Agonist, GSK1016790A
A cell-permeable, potent, selective agonist of TRPV4 channel. Enhances Ca2+ flux in a variety of human and mouse cells (EC50 = 2.1 nM for human TRPV4).
MilliporeSigma™ Calbiochem™ ALDH3A1 Inhibitor, CB29
A cell permeable, selective, reversible, substrate-binding site directed inhibitor of aldehyde dehydrogenase ALDH3A1 (Ki = 4.7 μM, IC50 = 16 μM).
MilliporeSigma™ Calbiochem™ Cathepsin K Inhibitor II
The Cathepsin K Inhibitor II controls the biological activity of Cathepsin K. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Interferon-α-IFNα-R Interaction Inhibitor
The Interferon-α-IFNα-R Interaction Inhibitor controls the biological activity of Interferon-α-IFNα-R.
MilliporeSigma™ Calbiochem™ Phosphatase Inhibitor Cocktail Set III, Lyophilized
The Phosphatase Inhibitor Cocktail Set III, Lyophilized controls the activity of Phosphatase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Bortezomib
Bortezomib, CAS 179324-69-7, is a cell-permeable, selective, slowly reversible inhibitor of 20S proteasome β5 ChTL/chymotrypsin- over β1 CL/caspase- and β2 TL/trypsin-like activity.
MilliporeSigma™ Calbiochem™ 3-Nitropropionic acid
A cell-permeable, irreversible inactivator (≈3 mM) of succinate dehydrogenase that upon oxidation by Complex II forms a covalent adduct with Arg297 in the active site of the enzyme.
MilliporeSigma™ Calbiochem™ Calpain Inhibitor IV
The Calpain Inhibitor IV controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Nα-Tosyl-Phe Chloromethyl Ketone
Irreversible inhibitor of chymotrypsin
MilliporeSigma™ Calbiochem™ Caspase Inhibitor III
The Caspase Inhibitor III, also referenced under CAS 634911-80-1, controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Nimodipine
An L-type Ca2+ channel blocker.
MilliporeSigma™ Calbiochem™ Cisplatin
Reported to sensitize glioma cells to TNF-α-induced apoptosis.
MilliporeSigma™ Calbiochem™ Ras/Rac Transformation Blocker, SCH 51344
Ras/Rac Transformation Blocker, SCH 51344, CAS 171927-40-5, is a blocker of Ras-induced malignant transformation and Ras/Rac-dependent dissociation of EMS1 from the actin-myosin II complex.
MilliporeSigma™ Calbiochem™ PFKFB3 Inhibitor III, YN1
A cell-permeable, potent and competitive inhibitor of fructose-2,6-bisphosphatase 3 (PFKFB3; IC50 = 670 nM).